- Author:
- Eduardo Anitua
- Gorka Orive
- B de la Sen Corcuera
- R M Sánchez Ávila
- P Heredia
- F Muruzabal
- J Merayo-Lloves
Progress in the use of plasma rich in growth factors in ophthalmology: from ocular surface to ocular fundus
Expert Opin Biol Ther. 2022 Jan;22(1):31-45. The use of blood derivatives and especially Plasma rich in growth factors (PRGF), for regenerative purposes has been a common trend along the last decades in the field of oral surgery, dermatology, orthopedics, and more recently in ophthalmology.
- Author:
- Eduardo Anitua
- Ronald M Sánchez-Ávila
- Edmar Uribe-Badillo
- Carlos Fernández-Vega González
- Francisco Muruzabal
- Borja de la Sen-Corcuera
- Begoña Baamonde
- Luis M Quirós
- Jesús Merayo-Lloves
Use of Plasma Rich in Growth Factors and ReGeneraTing Agent Matrix for the Treatment of Corneal Diseases
Vision (Basel). 2021 Jul 2;5(3):34. This study aimed to investigate the use of Plasma Rich in Growth Factors (PRGF) associated with tissue ReGeneraTing Agent (RGTA) drops for the treatment of noninfectious corneal ulcers
- Author:
- Rahhal-Ortuño M
- Fernández-Santodomingo AS
- Martínez-Rubio C
- Barranco-González H
- Almor-Palacios I
- Rodrigo-Hernández A.
Use of plasma rich in growth factors (PRGF-Endoret®) fibrin membrane to cover corneal dellen
Rom J Ophthalmol. 2021 Jul-Sep;65(3):293-295. Corneal dellen appeared as a complication after perilimbal conjunctival papilloma dissection in a six-year-old patient.
- Author:
- Suárez-Barrio C
- Del Olmo-Aguado S
- García-Pérez E
- Fernández-Vega-Cueto L
- Fernández-Vega Cueto A
- Baamonde-Arbaiza B
- Fernández-Vega L
- Merayo-Lloves J.
Plasma Rich in Growth Factors Promotes Autophagy in ARPE19 Cells in Response to Oxidative Stress Induced by Blue Light
Biomolecules. 2021 Jun 28;11(7):954. Age-related macular degeneration (AMD) causes the degeneration of photoreceptors and retinal cells leading to vision loss in older subjects. Among possible exogenous risk factors, it has been recently proposed that long-term exposure to blue light could aggravate the course of AMD. In the search for therapeutic options, plasma rich in growth factors (PRGF) has been shown to enhance cell antioxidant pathways and protect photoreceptors against the harm produced by blue light, although its mechanism of action remains unknown.
- Author:
- Eduardo Anitua
- Gorka Orive
Platelet-rich therapies as an emerging platform for regenerative medicine
Expert Opin Biol Ther. 2021 Dec;21(12):1603-1608. The combination of human plasma components with the multiple secretome from platelets has provided a new biological tool that is shaping a new future for its direct application in tissue regeneration as well as in cell culture and advanced therapy by means of its use as a clinical-grade supplement.
- Author:
- Eduardo Anitua
- Ronald M Sánchez-Ávila
- Natalia Vázquez
- Manuel Chacón
- Mairobi Persinal-Medina
- Agustín Brea-Pastor
- Silvia Berisa-Prado
- Luis Fernández-Vega-Cueto
- lvaro Meana
- Jesús Merayo-Lloves
Fibrin-Plasma Rich in Growth Factors Membrane for the Treatment of a Rabbit Alkali-Burn Lesion
Int J Mol Sci. 2021 May 25;22(11):5564. The purpose of this work is to describe the use of Fibrin-Plasma Rich in Growth Factors (PRGF) membranes for the treatment of a rabbit alkali-burn lesion
- Author:
- Giralt IM
- Bueis AB
- Zarzuelo AH
- Moreno JVD
- Milner RM
- Corcuera BS.
Recurrent pterygium resection associated to fibrin membrane graft: report of two cases
Rev Bras Oftalmol.2021;80(2):146-150 We propose a novel surgical technique in cases of aggressive recurrent pterygium non-subsidiary of treatment with conjunctival autografts or antimetabolites.
- Author:
- Eduardo Anitua
- Ander Pino
- Libe Aspe
- MaIsabel Martínez
- Adrian García
- Felipe Goñi
- María Troya
Anti-inflammatory effect of different PRGF formulations on cutaneous surface
J Tissue Viability. 2021 May;30(2):183-189. Cutaneous autoimmune and inflammatory diseases are a major burden of global disease and many lack effective treatments that can derive in different dermatoses like atopic dermatitis. Despite the increase prevalence and the high health-care costs worldwide, the heterogeniety and multifactoriality of these diseases mean that effective treatment options are scarce.
- Author:
- Eduardo Anitua
- Roberto Prado
Platelet-Rich Plasma for Chronic Plantar Fasciitis: as with any other treatment, a comprehensive protocol is necessary
J Foot Ankle Surg. 2021 Mar-Apr;60(2):428. In this appealing clinical trial, the authors compare the pain and functional outcomes of single injection of platelet-rich plasma (PRP), corticosteroids (CS), and placebo for the treatment of patients diagnosed with chronic plantar fasciitis
- Author:
- Eduardo Anitua
- Gorka Orive
- Alfonso L Sabater
- Hazem M Mousa
- Xavier Quinones
- Felipe Valenzuela
- Ronald Mauricio Sanchez Avila
- Jesús Merayo
- Victor L Perez
Use of autologous plasma rich in growth factors fibrin membrane in the surgical management of ocular surface diseases
Int Ophthalmol. 2021 Jul;41(7):2347-2358. To evaluate the safety and efficacy of the surgical use of autologous plasma rich in growth factors fibrin membrane (mPRGF) in improving corneal wound healing and regeneration in a variety of complex ocular surface defects.

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