Español
Français
Deutsch
Italiano
Português
- Author:
- Eduardo Anitua
- Ander Pino
- Libe Aspe
- MaIsabel Martínez
- Adrian García
- Felipe Goñi
- María Troya
Anti-inflammatory effect of different PRGF formulations on cutaneous surface
J Tissue Viability. 2021 May;30(2):183-189. Cutaneous autoimmune and inflammatory diseases are a major burden of global disease and many lack effective treatments that can derive in different dermatoses like atopic dermatitis. Despite the increase prevalence and the high health-care costs worldwide, the heterogeniety and multifactoriality of these diseases mean that effective treatment options are scarce.
- Author:
- Eduardo Anitua
- Roberto Prado
Platelet-Rich Plasma for Chronic Plantar Fasciitis: as with any other treatment, a comprehensive protocol is necessary
J Foot Ankle Surg. 2021 Mar-Apr;60(2):428. In this appealing clinical trial, the authors compare the pain and functional outcomes of single injection of platelet-rich plasma (PRP), corticosteroids (CS), and placebo for the treatment of patients diagnosed with chronic plantar fasciitis
- Author:
- Eduardo Anitua
- Gorka Orive
- Alfonso L Sabater
- Hazem M Mousa
- Xavier Quinones
- Felipe Valenzuela
- Ronald Mauricio Sanchez Avila
- Jesús Merayo
- Victor L Perez
Use of autologous plasma rich in growth factors fibrin membrane in the surgical management of ocular surface diseases
Int Ophthalmol. 2021 Jul;41(7):2347-2358. To evaluate the safety and efficacy of the surgical use of autologous plasma rich in growth factors fibrin membrane (mPRGF) in improving corneal wound healing and regeneration in a variety of complex ocular surface defects.
- Author:
- Ruzafa N
- Pereiro X
- Fonollosa A
- Araiz J
- Acera A
- Vecino E.
Plasma Rich in Growth Factors (PRGF) Increases the Number of Retinal Müller Glia in Culture but Not the Survival of Retinal Neurons
Front Pharmacol. 2021 Mar 9;12:606275. Plasma rich in growth factors (PRGF) is a subtype of platelet-rich plasma (PRP) that stimulates tissue regeneration and may promote neuronal survival. It has been employed in ophthalmology to achieve tissue repair in some retinal pathologies, although how PRGF acts in the retina is still poorly understood. As a part of the central nervous system, the retina has limited capacity for repair capacity following damage, and retinal insult can provoke the death of retinal ganglion cells (RGCs), potentially producing irreversible blindness. RGCs are in close contact with glial cells, such as Müller cells, that help maintain homeostasis in the retina.
- Author:
- Eduardo Anitua
- María de la Fuente
- Francisco Muruzábal
- Jesús Merayo-Lloves
Stability of freeze-dried plasma rich in growth factors eye drops stored for 3 months at different temperature conditions
Eur J Ophthalmol. 2021 Mar;31(2):354-360. The purpose of this study was to analyze the biological content and activity of freeze-dried plasma rich in growth factors eye drops after their storage at 4°C and at room temperature for 3 months with respect to fresh samples (time 0)
- Author:
- Eduardo Anitua
- Ander Pino
- Mar Zalduendo
Long-term stability of a novel platelet-rich plasma-based topical serum for cutaneous applications
J Cosmet Dermatol. 2021 Mar;20(3):854-861. Skin alterations are usually related to chronic diseases that demand sustained and long-term dosages; hence, it is pivotal that the stability of treatments is preserved. A novel storable and endogenous topical serum (ES) based on the patient's own blood has been recently developed
- Author:
- Ruzafa N
- Pereiro X
- Fonollosa A
- Araiz J
- Acera A
- Vecino E.
The Effect of Plasma Rich in Growth Factors on Microglial Migration, Macroglial Gliosis and Proliferation, and Neuronal Survival
Front Pharmacol. 2021 Feb 26;12:606232. Plasma rich in growth factors (PRGF) is a subtype of platelet-rich plasma that has being employed in the clinic due to its capacity to accelerate tissue regeneration. Autologous PRGF has been used in ophthalmology to repair a range of retinal pathologies with some efficiency. In the present study, we have explored the role of PRGF and its effect on microglial motility, as well as its possible pro-inflammatory effects. Organotypic cultures from adult pig retinas were used to test the effect of the PRGF obtained from human as well as pig blood. Microglial migration, as well as gliosis, proliferation and the survival of retinal ganglion cells (RGCs) were analyzed by immunohistochemistry.
- Author:
- Eduardo Anitua
- María de la Fuente
- Francisco Muruzabal
- Jesús Merayo-Lloves
Development and optimization of a personalized fibrin membrane derived from the plasma rich in growth factors technology
Exp Eye Res. 2021 Feb:203:108402. To develop and characterize a new type of plasma rich in growth factors (PRGF) membrane for patients in which immune system is involved in the disease etiology
- Author:
- Eduardo Anitua
- Ronald M Sanchez-Avila
- Edmar E Uribe-Badillo
- Javier Fernández-Vega Sanz
- Francisco Muruzabal
- Nancy Jurado
- Belén Alfonso-Bartolozzi
- Jose F Alfonso
- Begoña Baamonde
- Jesus Merayo-Lloves
Plasma rich in growth factors versus Mitomycin C in photorefractive keratectomy
Medicine (Baltimore). 2021 Jan 22;100(3):e24139. To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) in photorefractive keratectomy (PRK) versus Mitomycin C (MMC).This is a comparative, longitudinal and retrospective case-control study (MMC vs PRGF), in patients with a spherical correction from -0.25 to -8.00 D and cylinder correction from -0.25 to -3.00
- Author:
- Eduardo Anitua
- Sabino Padilla
- Mikel Sánchez
- Victor Vaquerizo
- Gerard A Malanga
- Nicolás Fiz
- Juan Azofra
- Christopher J Rogers
- Gonzalo Samitier
- Steven Sampson
- Roberto Seijas
- Ricardo Elorriaga
- Jack Taunton
- Frank Boehm
- Roberto Prado
- Ramón Cugat
Platelet-Rich Plasma Applications for Achilles Tendon Repair: A Bridge between Biology and Surgery
Int J Mol Sci. 2021 Jan 15;22(2):824. Achilles tendon ruptures are very common tendon ruptures and their incidence is increasing in modern society, resulting in work incapacity and months off sport, which generate a need for accelerated and successful therapeutic repair strategy. Platelet-rich plasma (PRP) is emerging as adjuvant human blood-derived constructs to assist Achilles tendon rupture treatment