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Articles of Regenerative medicine

Expert Opin Biol Ther. 2022 Jan;22(1):31-45. The use of blood derivatives and especially Plasma rich in growth factors (PRGF), for regenerative purposes has been a common trend along the last decades in the field of oral surgery, dermatology, orthopedics, and more recently in ophthalmology.

  • Author:
  • Eduardo Anitua
  • Ronald M Sánchez-Ávila
  • Edmar Uribe-Badillo
  • Carlos Fernández-Vega González
  • Francisco Muruzabal
  • Borja de la Sen-Corcuera
  • Begoña Baamonde
  • Luis M Quirós
  • Jesús Merayo-Lloves

Vision (Basel). 2021 Jul 2;5(3):34. This study aimed to investigate the use of Plasma Rich in Growth Factors (PRGF) associated with tissue ReGeneraTing Agent (RGTA) drops for the treatment of noninfectious corneal ulcers

  • Author:
  • Suárez-Barrio C
  • Del Olmo-Aguado S
  • García-Pérez E
  • Fernández-Vega-Cueto L
  • Fernández-Vega Cueto A
  • Baamonde-Arbaiza B
  • Fernández-Vega L
  • Merayo-Lloves J.

Biomolecules. 2021 Jun 28;11(7):954. Age-related macular degeneration (AMD) causes the degeneration of photoreceptors and retinal cells leading to vision loss in older subjects. Among possible exogenous risk factors, it has been recently proposed that long-term exposure to blue light could aggravate the course of AMD. In the search for therapeutic options, plasma rich in growth factors (PRGF) has been shown to enhance cell antioxidant pathways and protect photoreceptors against the harm produced by blue light, although its mechanism of action remains unknown.

  • Author:
  • Eduardo Anitua
  • Ronald M Sánchez-Ávila
  • Natalia Vázquez
  • Manuel Chacón
  • Mairobi Persinal-Medina
  • Agustín Brea-Pastor
  • Silvia Berisa-Prado
  • Luis Fernández-Vega-Cueto
  • lvaro Meana
  • Jesús Merayo-Lloves

Int J Mol Sci. 2021 May 25;22(11):5564. The purpose of this work is to describe the use of Fibrin-Plasma Rich in Growth Factors (PRGF) membranes for the treatment of a rabbit alkali-burn lesion

J Tissue Viability. 2021 May;30(2):183-189. Cutaneous autoimmune and inflammatory diseases are a major burden of global disease and many lack effective treatments that can derive in different dermatoses like atopic dermatitis. Despite the increase prevalence and the high health-care costs worldwide, the heterogeniety and multifactoriality of these diseases mean that effective treatment options are scarce.

  • Author:
  • Eduardo Anitua
  • Gorka Orive
  • Alfonso L Sabater
  • Hazem M Mousa
  • Xavier Quinones
  • Felipe Valenzuela
  • Ronald Mauricio Sanchez Avila
  • Jesús Merayo
  • Victor L Perez

Int Ophthalmol. 2021 Jul;41(7):2347-2358. To evaluate the safety and efficacy of the surgical use of autologous plasma rich in growth factors fibrin membrane (mPRGF) in improving corneal wound healing and regeneration in a variety of complex ocular surface defects.