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Articles of Regenerative medicine

  • Author:
  • Eduardo Anitua
  • Diez GG
  • Castellanos N
  • Vázquez C
  • Galindo-Villardón P
  • Alkhraisat MH

Narrow dental implants are commonly used to restore narrow alveolar ridges. Although the good performance of narrow dental implants supporting multiple prostheses has been repeatedly demonstrated, there are few studies analyzing their performance in a long-term follow-up together with the influence of the loading protocol. Thus, the objective was to assess the influence of implant loading protocol (immediate vs delayed) on the long-term outcomes of 3.0-mm-diameter dental implants supporting fixed multiple prostheses.

  • Author:
  • Eduardo Anitua
  • Antonio Ríos
  • Homid Fahandezh-Saddi Díaz
  • Manuel Villanueva Martinez
  • Roberto Prado
  • Sabino Padilla

The application of the counter-torque technique has been proposed as a conservative and atraumatic alternative for the explantation of nonmobile dental implants. The objective of this report is to assess the performance of this technique in a large number of patients.

  • Author:
  • Eduardo Anitua
  • Mohammad H. Alkhraisat
  • Mar Zalduendo
  • María Troya
  • Roberto Tierno

Scaffolds should have controllable degradation rate and allow cells to produce their own extracellular matrix. Platelet rich plasma (PRP) is a source of autologous growth factors and proteins embedded in a 3D fibrin scaffold. There is no consensus regarding the obtaining conditions and composition of PRPs.

  • Author:
  • Eduardo Anitua
  • Ronald M Sánchez-Ávila
  • Carlos A Robayo-Esper
  • Eva Villota-Deleu
  • Álvaro Fernández-Vega Sanz
  • Álvaro Fernández-Vega González
  • Borja de la Sen-Corcuera
  • Jesús Merayo-Lloves

The aim of this study was to evaluate the use of PRGF (plasma rich in growth factors) as an adjuvant to PPV (pars plana vitrectomy) in recurrent, persistent, or poor prognosis MH (macular hole). Patients with MH were treated with PPV plus adjuvant therapy (PRGF membrane (mPRGF) and injectable liquid PRGF (iPRGF)).

Skin injury and wound healing is an inevitable event during lifetime. However, several complications may hamper the regeneration of the cutaneous tissue and lead to a chronic profile that prolongs patient recovery. Platelet-rich plasma is rising as an effective and safe alternative to the management of wounds

  • Author:
  • Eduardo Anitua
  • Gorka Orive
  • Miriam Idoipe
  • Borja de la Sen-Corcuera
  • Ronald M Sánchez-Ávila
  • Carmen Sánchez-Pérez
  • María Satué
  • Antonio Sánchez-Pérez
  • Francisco Muruzabal
  • Luis Pablo

This prospective and comparative study aimed to compare the use of a conjunctival autograft (CAG), plasma rich in growth factors fibrin membrane (mPRGF) or amniotic membrane transplantation (AMT) in primary pterygium surgery.

  • Author:
  • Eduardo Anitua
  • María Troya
  • Roberto Tierno
  • Mar Zalduendo
  • Mohammad H. Alkhraisat

Fibrin, as a physiological scaffold, presents many advantages compared to synthetic materials, such as controllable degradation, non-toxic byproducts, and excellent biocompatibility. The use of stem cells along with the biomimicking scaffolds and signalling factors would complete the triad of the tissue engineering approach

  • Author:
  • Eduardo Anitua
  • Sabino Padilla
  • Alan T Nurden
  • Roberto Prado
  • Paquita Nurden

Evolution, from invertebrates to mammals, has yielded and shaped immunoclotting as a defense and repair response against trauma and infection. This mosaic of immediate and local wound-sealing and pathogen-killing mechanisms results in survival, restoration of homeostasis, and tissue repair.