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Articles of Regenerative medicine

Over the last three decades, there has been special interest in developing drugs that mimic the characteristics of natural tears for use it in the treatment of several ocular surface disorders. Interestingly, the composition of blood plasma is very similar to tears. Therefore, different blood-derived products like autologous serum (AS) and plasma rich in growth factors (PRGF) have been developed for the treatment of diverse ocular pathologies.

  • Author:
  • Eduardo Anitua
  • Fernando Kirchner
  • Isidro Milani
  • Alex Martinez
  • Nicolas Kirchner-Bossi
  • Roberto Prado
  • Sabino Padilla

Plasma rich in growth factors (PRGF) is a leukocyte-free platelet-rich plasma (PRP) that is an effective biological approach to tissue repair and has been demonstrated to significantly improve multiple conditions, including low back pain and degenerative disc pathology

  • Author:
  • Eduardo Anitua
  • Ronald M Sánchez-Ávila
  • Edmar Uribe-Badillo
  • Carlos Fernández-Vega González
  • Francisco Muruzabal
  • Borja de la Sen-Corcuera
  • Begoña Baamonde
  • Luis M Quirós
  • Jesús Merayo-Lloves

This study aimed to investigate the use of Plasma Rich in Growth Factors (PRGF) associated with tissue ReGeneraTing Agent (RGTA) drops for the treatment of noninfectious corneal ulcers

Cutaneous autoimmune and inflammatory diseases are a major burden of global disease and many lack effective treatments that can derive in different dermatoses like atopic dermatitis. Despite the increase prevalence and the high health-care costs worldwide, the heterogeniety and multifactoriality of these diseases mean that effective treatment options are scarce.

  • Author:
  • Eduardo Anitua
  • Gorka Orive
  • Alfonso L Sabater
  • Hazem M Mousa
  • Xavier Quinones
  • Felipe Valenzuela
  • Ronald Mauricio Sanchez Avila
  • Jesús Merayo
  • Victor L Perez

To evaluate the safety and efficacy of the surgical use of autologous plasma rich in growth factors fibrin membrane (mPRGF) in improving corneal wound healing and regeneration in a variety of complex ocular surface defects.