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- Autor:
- Eduardo Anitua
- Ronald M Sánchez-Ávila
- Carlos A Robayo-Esper
- Eva Villota-Deleu
- Álvaro Fernández-Vega Sanz
- Álvaro Fernández-Vega González
- Borja de la Sen-Corcuera
- Jesús Merayo-Lloves
Plasma Rich in Growth Factors in Macular Hole Surgery
Clin Pract. 2022 Jan 10;12(1):57-69. The aim of this study was to evaluate the use of PRGF (plasma rich in growth factors) as an adjuvant to PPV (pars plana vitrectomy) in recurrent, persistent, or poor prognosis MH (macular hole). Patients with MH were treated with PPV plus adjuvant therapy (PRGF membrane (mPRGF) and injectable liquid PRGF (iPRGF)).
- Autor:
- Eduardo Anitua
- Ander Pino
- Victoria Muñoz
- Libe Aspe
- Roberto Tierno
- Adrian García-Salvador
- Felipe Goñi-de-Cerio
In vitro and in vivo Effect of Platelet-Rich Plasma-Based Autologous Topical Serum on Cutaneous Wound Healing
Skin Pharmacol Physiol. 2022;35(1):51-64. Skin injury and wound healing is an inevitable event during lifetime. However, several complications may hamper the regeneration of the cutaneous tissue and lead to a chronic profile that prolongs patient recovery. Platelet-rich plasma is rising as an effective and safe alternative to the management of wounds
- Autor:
- Eduardo Anitua
- Gorka Orive
- Miriam Idoipe
- Borja de la Sen-Corcuera
- Ronald M Sánchez-Ávila
- Carmen Sánchez-Pérez
- María Satué
- Antonio Sánchez-Pérez
- Francisco Muruzabal
- Luis Pablo
Membrane of Plasma Rich in Growth Factors in Primary Pterygium Surgery Compared to Amniotic Membrane Transplantation and Conjunctival Autograft
J Clin Med. 2021 Dec 6;10(23):5711. This prospective and comparative study aimed to compare the use of a conjunctival autograft (CAG), plasma rich in growth factors fibrin membrane (mPRGF) or amniotic membrane transplantation (AMT) in primary pterygium surgery.
- Autor:
- Eduardo Anitua
- Mohammad H. Alkhraisat
- María Troya
- Roberto Tierno
- Mar Zalduendo
The Effectiveness of Platelet-Rich Plasma as a Carrier of Stem Cells in Tissue Regeneration: A Systematic Review of Pre-Clinical Research
Cells Tissues Organs. 2021;210(5-6):339-350. Fibrin, as a physiological scaffold, presents many advantages compared to synthetic materials, such as controllable degradation, non-toxic byproducts, and excellent biocompatibility. The use of stem cells along with the biomimicking scaffolds and signalling factors would complete the triad of the tissue engineering approach
- Autor:
- Eduardo Anitua
- Sabino Padilla
- Alan T Nurden
- Roberto Prado
- Paquita Nurden
Healing through the lens of immunothrombosis: Biology-inspired, evolution-tailored, and human-engineered biomimetic therapies
Biomaterials. 2021 Dec:279:121205. Evolution, from invertebrates to mammals, has yielded and shaped immunoclotting as a defense and repair response against trauma and infection. This mosaic of immediate and local wound-sealing and pathogen-killing mechanisms results in survival, restoration of homeostasis, and tissue repair.
- Autor:
- Eduardo Anitua
- Ander Pino
- Francisco Muruzabal
- Roberto Prado
- Mikel Azkargorta
- Felix Elortza
- Jesús Merayo-Lloves
Proteomic Characterization of Plasma Rich in Growth Factors and Undiluted Autologous Serum
Int J Mol Sci. 2021 Nov 10;22(22):12176. Over the last three decades, there has been special interest in developing drugs that mimic the characteristics of natural tears for use it in the treatment of several ocular surface disorders. Interestingly, the composition of blood plasma is very similar to tears. Therefore, different blood-derived products like autologous serum (AS) and plasma rich in growth factors (PRGF) have been developed for the treatment of diverse ocular pathologies.
- Autor:
- Figueroa MS
- Mora Cantallops A
- Virgili G
- Govetto A
Long-term results of autologous plasma as adjuvant to pars plana vitrectomy in the treatment of high myopic full-thickness macular holes
Eur J Ophthalmol. 2021 Sep;31(5):2612-2620. To analyse the feasibility and efficacy of a novel autologous plasma rich in growth factor (PRGF) preparation as adjuvant to pars plana vitrectomy and internal limiting membrane peel in high myopic full-thickness macular hole (FTMH).
- Autor:
- Jesús Merayo Lloves
- Berisa-Prado S
- Vázquez N
- Chacón M
- Persinal-Medina M
- Alonso-Alonso S
- Baamonde B
- Alfonso JF
- Fernández-Vega-Cueto L
- Meana Á.
Mini Cleanroom for the Manufacture of Advanced Therapy Medicinal Products (ATMP): Bioengineered Corneal Epithelium
Pharmaceutics. 2021 Aug 17;13(8):1282. Among several requirements for the manufacture of Advanced Therapy Medicinal Products (ATMP) are: following the guidelines of a pharmaceutical quality system, complying with Good Manufacturing Practice (GMP) and access to a cleanroom fulfilling strict environmental conditions (Class A work area and Class B environment). This makes ATMP expensive.
- Autor:
- Eduardo Anitua
- Sabino Padilla
- Fernando Kirchner
- Isidro Milani
- Alex Martinez
- Nicolas Kirchner-Bossi
- Roberto Prado
Plasma Rich in Growth Factors (PRGF) in the Treatment of Cervical and Lumbar Back Pain: A Retrospective Observational Clinical Study
Pain Physician. 2021 Aug;24(5):E649-E660. Plasma rich in growth factors (PRGF) is a leukocyte-free platelet-rich plasma (PRP) that is an effective biological approach to tissue repair and has been demonstrated to significantly improve multiple conditions, including low back pain and degenerative disc pathology
- Autor:
- Eduardo Anitua
- Ander Pino
- Victoria Muñoz
- Carmen Martinez
- Begoña Echevarria
- Varlan Lacramioara
An Autologous Protein-Based Topical Ointment for Hard-to-Heal Skin Wounds: A Multiple Case Series
J Wound Ostomy Continence Nurs. 2021 Jul-Aug;48(4):350-355. There is increasing evidence regarding the wound healing potential of platelet-derived autologous by-products. We provide preliminary data regarding the use of a new plasma rich in growth factors-derived autologous topical ointment for the management of hard-to-heal wounds