- Autor:
- Eduardo Anitua
- Gorka Orive
- Mar Zalduendo
- María Troya
- Itsasne Erezuma
- Izeia Lukin
- Raquel Hernáez-Moya
Composite alginate-gelatin hydrogels incorporating PRGF enhance human dental pulp cell adhesion, chemotaxis and proliferation
The increasing prevalence of tissue injuries is fueling the development of autologous biological treatments for regenerative medicine. Here, we investigated the potential of three different bioinks based on the combination of gelatin and alginate (GA), enriched in either hydroxyapatite (GAHA) or hydroxyapatite and PRGF (GAHAP), as a favorable microenvironment for human dental pulp stem cells (DPSCs)
- Autor:
- Eduardo Anitua
- Mohammad H. Alkhraisat
- Roberto Tierno
Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data
The role of prophylactic vitamin D supplementation in prevention and treatment of respiratory infections and other related pathologies has been extensively explored with conflicting results. The aim of this systematic review and meta-analysis was to evaluate the prophylactic and therapeutic effects of vitamin D administration on respiratory infections.
- Autor:
- Eduardo Anitua
Implant Dentistry from One-Way Direction to the Reversibility of the Osseointegration
Nowadays, implant dentistry has social, economic, and clinical values. It is one of the economic motors of society. The reliability and high success rate of implant-based oral rehabilitation are fascinating, making this option predictable and safe.[1] However, dealing with an implant failure is frustrating for both clinicians and patients. For this reason, moving implant dentistry from a one-way direction to treatment reversibility would improve the management of failure cases with minimally invasive measures.
- Autor:
- Eduardo Anitua
- Mohammad H. Alkhraisat
- Mar Zalduendo
- María Troya
- Roberto Tierno
The inclusion of leukocytes into platelet rich plasma reduces scaffold stability and hinders extracellular matrix remodelling
Scaffolds should have controllable degradation rate and allow cells to produce their own extracellular matrix. Platelet rich plasma (PRP) is a source of autologous growth factors and proteins embedded in a 3D fibrin scaffold. There is no consensus regarding the obtaining conditions and composition of PRPs.
- Autor:
- Eduardo Anitua
- Ronald M Sánchez-Ávila
- Carlos A Robayo-Esper
- Eva Villota-Deleu
- Álvaro Fernández-Vega Sanz
- Álvaro Fernández-Vega González
- Borja de la Sen-Corcuera
- Jesús Merayo-Lloves
Plasma Rich in Growth Factors in Macular Hole Surgery
The aim of this study was to evaluate the use of PRGF (plasma rich in growth factors) as an adjuvant to PPV (pars plana vitrectomy) in recurrent, persistent, or poor prognosis MH (macular hole). Patients with MH were treated with PPV plus adjuvant therapy (PRGF membrane (mPRGF) and injectable liquid PRGF (iPRGF)).
- Autor:
- Eduardo Anitua
- Ander Pino
- Victoria Muñoz
- Libe Aspe
- Roberto Tierno
- Adrian García-Salvador
- Felipe Goñi-de-Cerio
In vitro and in vivo Effect of Platelet-Rich Plasma-Based Autologous Topical Serum on Cutaneous Wound Healing
Skin injury and wound healing is an inevitable event during lifetime. However, several complications may hamper the regeneration of the cutaneous tissue and lead to a chronic profile that prolongs patient recovery. Platelet-rich plasma is rising as an effective and safe alternative to the management of wounds
- Autor:
- Eduardo Anitua
- Aintzane Torre
- Mohammad H. Alkhraisat
- Asier Eguia
- Laura Piñas
- Beatriz Anitua
Dental implants survival after nasal floor elevation: a systematic review
The aim of this work is to assess the clinical outcomes of implants placed after a nasal floor elevation procedure
- Autor:
- Eduardo Anitua
- Gorka Orive
- Miriam Idoipe
- Borja de la Sen-Corcuera
- Ronald M Sánchez-Ávila
- Carmen Sánchez-Pérez
- María Satué
- Antonio Sánchez-Pérez
- Francisco Muruzabal
- Luis Pablo
Membrane of Plasma Rich in Growth Factors in Primary Pterygium Surgery Compared to Amniotic Membrane Transplantation and Conjunctival Autograft
This prospective and comparative study aimed to compare the use of a conjunctival autograft (CAG), plasma rich in growth factors fibrin membrane (mPRGF) or amniotic membrane transplantation (AMT) in primary pterygium surgery.
- Autor:
- Eduardo Anitua
- Mohammad H. Alkhraisat
- María Troya
- Roberto Tierno
- Mar Zalduendo
The Effectiveness of Platelet-Rich Plasma as a Carrier of Stem Cells in Tissue Regeneration: A Systematic Review of Pre-Clinical Research
Fibrin, as a physiological scaffold, presents many advantages compared to synthetic materials, such as controllable degradation, non-toxic byproducts, and excellent biocompatibility. The use of stem cells along with the biomimicking scaffolds and signalling factors would complete the triad of the tissue engineering approach
- Autor:
- Eduardo Anitua
- Sabino Padilla
- Alan T Nurden
- Roberto Prado
- Paquita Nurden
Healing through the lens of immunothrombosis: Biology-inspired, evolution-tailored, and human-engineered biomimetic therapies
Evolution, from invertebrates to mammals, has yielded and shaped immunoclotting as a defense and repair response against trauma and infection. This mosaic of immediate and local wound-sealing and pathogen-killing mechanisms results in survival, restoration of homeostasis, and tissue repair.