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Articoli

Enhancing the correlation between in vitro and in vivo experiments in dental implant osseointegration: investigating the role of Ca ions
PMID: 38412455

J Mater Chem B. 2024 Mar 13;12(11):2831-2842. This study delves into the osteogenic potential of a calcium-ion modified titanium implant surface, unicCa, employing state-of-the-art proteomics techniques both in vitro (utilizing osteoblasts and macrophage cell cultures) and in vivo (in a rabbit condyle model). When human osteoblasts (Hobs) were cultured on unicCa surfaces, they displayed a marked improvement in cell adhesion and differentiation compared to their unmodified counterparts. The proteomic analysis also revealed enrichment in functions associated with cell migration, adhesion, extracellular matrix organization, and proliferation.

Biochemical and biomechanical characterization of an autologous protein-based fibrin sealant for regenerative medicine
PMID: 38456966

J Mater Sci Mater Med. 2024 Mar 8;35(1):15 Accidental events or surgical procedures usually lead to tissue injury. Fibrin sealants have proven to optimize the healing process but have some drawbacks due to their allogeneic nature. Autologous fibrin sealants present several advantages. The aim of this study is to evaluate the performance of a new autologous fibrin sealant based on Endoret®PRGF® technology (E-sealant). One of the most widely used commercial fibrin sealants (Tisseel®) was included as comparative Control.

[5.5 mm implant. A solution for severe atrophies without sacrificing predictability]
PMID: 38390603

Rev Cient Odontol (Lima). 2023 Dec 26;10(4):e137. The rehabilitation of areas of the maxilla and mandible with extreme resorption is a fact of increased presence in our dental practice. Surgical techniques such as short and extra-short implants facilitate the resolution of these clinical cases. In this clinical case report we develop a case rehabilitated using a 5.5 mm long implant and we provide a biomechanical study of the behaviour of implants with these characteristics.

Sleep bruxism and sleep respiratory disorders in children and adolescents: A systematic review.
PMID: 38098259 Review.

Oral Dis. 2024 Sep;30(6):3610-3637. Sleep bruxism (SB) is a repetitive rhythmic and nonrhythmic activity. It can be a comorbid condition for other disorders, such as sleep breathing disorders (SBD). However, a clear causal link between these factors is yet to be established. Moreover, this relationship is even more unknown in children. Thus, this systematic review aimed to determine the relationship between SB and SBD in children and teenagers and consolidate the current knowledge about the possible association between both phenomena at the pediatric age.

Does orthognathic surgery have an incidentally beneficial effect on mild or asymptomatic sleep apnoea?
  • Autore:
  • Eduardo Anitua
  • Valls-Ontañón A
  • Giralt-Hernando M
  • Zamora-Almeida G
  • Mazarro-Campos A
  • Hernández-Alfaro F.
PMID: 37211459

Int J Oral Maxillofac Surg. 2023 Dec;52(12):1255-1261. A prospective study was performed to assess the effect of orthognathic surgery on mild obstructive sleep apnoea (OSA) in patients with an underlying dentofacial deformity treated for occlusal and/or aesthetic reasons. As the main outcome variables, changes in upper airway volume and apnoea-hypopnoea index (AHI) were evaluated at 1 and 12 months of follow-up, in patients undergoing orthognathic surgery with widening movements of the maxillomandibular complex. Descriptive, bivariate, and correlation analyses were performed; significance was set at P < 0.05. Eighteen patients diagnosed with mild OSA were enroled (mean age 39.8 ± 10.0 years). An overall upper airway volume widening of 46.7% after orthognathic surgery was observed at 12 months of follow-up.

Cellular composition modifies the biological properties and stability of platelet rich plasma membranes for tissue engineering
PMID: 37318048

J Biomed Mater Res A. 2023 Nov;111(11):1710-1721. Scaffolds should provide structural support for tissue regeneration, allowing their gradual biodegradation and interacting with cells and bioactive molecules to promote remodeling. Thus, the scaffold's intrinsic properties affect cellular processes involved in tissue regeneration, including migration, proliferation, differentiation, and protein synthesis. In this sense, due to its biological effect and clinical potential, Platelet Rich Plasma (PRP) fibrin could be considered a successful scaffold. Given the high variability in commercial PRPs formulations, this research focused on assessing the influence of cellular composition on fibrin membrane stability and remodeling cell activity.

A Multicenter Prospective Study on the Use of a Mandibular Advancement Device in the Treatment of Obstructive Sleep Apnea
  • Autore:
  • Eduardo Anitua
  • Mayoral P
  • Almeida GZ
  • Durán-Cantolla J
  • Alkhraisat MH
PMID: 37999010

Dent J (Basel). 2023 Oct 24;11(11):247. The main objective of this prospective study was the evaluation of 1 mm step titration of mandible advancement in the success of treating obstructive sleep apnea (OSA). For that, a multicenter prospective study was designed to recruit patients with OSA who were eligible to receive a mandibular advancement device.