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Articoli di Medicina rigenerativa

  • Autore:
  • Eduardo Anitua
  • Mohammad H. Alkhraisat
  • Sofía Fernández de Retana

Platelets. 2021 Feb 17;32(2):174-182. The application of platelet-rich plasma (PRP) in oral and maxillofacial surgery has been thoroughly studied in the last two decades. Currently, different types of PRP are applied in the clinical practice, being the presence or absence of leukocytes one of the classification criteria. However, there is poor evidence assessing the influence of the PRP composition in their efficacy.

  • Autore:
  • Eduardo Anitua
  • de la Fuente M
  • Del Olmo-Aguado S
  • Suarez-Barrio C
  • Merayo-Lloves J
  • Muruzabal F.

Clin Exp Ophthalmol. 2020 Aug;48(6):830-838. This study analysed the effectiveness of plasma rich in growth factors (PRGF) in reducing the oxidative stress induced by blue light exposition on retinal pigment epithelial (RPE) cells.

  • Autore:
  • Eduardo Anitua
  • Suárez-Barrio C
  • Del Olmo-Aguado S
  • García-Pérez E
  • de la Fuente M
  • Muruzabal F
  • Baamonde-Arbaiza B
  • Fernández-Vega-Cueto L
  • Fernández-Vega L
  • Merayo-Lloves J.

Int J Mol Sci. 2020 Feb 4;21(3):1021. Oxidative stress has a strong impact on the development of retinal diseases such as age-related macular degeneration (AMD). Plasma rich in growth factors (PRGF) is a novel therapeutic approach in ophthalmological pathologies. The aim of this study was to analyze the antioxidant effect of PRGF in retinal epithelial cells (EPR) in in vitro and ex vivo retinal phototoxicity models. In vitro analyses were performed on ARPE19 human cell line. Viability and mitochondrial status were assessed in order to test the primary effects of PRGF.

  • Autore:
  • Chaparro Tapias TA
  • Díaz Díaz AL
  • Secondi R
  • Coy Villamil H
  • Sánchez España JC.

Eur J Ophthalmol. 2019 Nov;29(6):654-658. Central graft ulceration is a rare complication of an orbital dermal fat graft caused by diminished blood supply to the implant. This study reports on the efficacy and safety of the use of a single subconjunctival injection of autologous platelet-rich plasma to rescue an ulcerated orbital dermal fat graft.

  • Autore:
  • Eduardo Anitua
  • Gorka Orive
  • Sánchez-Avila RM
  • Merayo-Lloves J
  • Fernández ML
  • Rodríguez-Gutiérrez LA
  • Rodríguez-Calvo PP
  • Fernández-Vega Cueto A
  • Muruzabal F

Int Med Case Rep J. 2018 May 1;11:97-103. To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) eye drops in patients with glaucoma with secondary ocular surface disorders (OSDs) due to surgeries and topical hypotensive drugs use.