{"id":40781,"date":"2023-06-01T15:35:00","date_gmt":"2023-06-01T14:35:00","guid":{"rendered":"https:\/\/www.btitrainingcenter.com\/development-of-a-new-plasma-rich-in-growth-factors-membrane-with-improved-optical-properties\/"},"modified":"2025-07-21T16:05:49","modified_gmt":"2025-07-21T15:05:49","slug":"development-of-a-new-plasma-rich-in-growth-factors-membrane-with-improved-optical-properties","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/pt-pt\/development-of-a-new-plasma-rich-in-growth-factors-membrane-with-improved-optical-properties\/","title":{"rendered":"Development of a new plasma rich in growth factors membrane with improved optical properties"},"content":{"rendered":"

[vc_row content_text_aligment=”left” row_background_lines=”no”][vc_column][vc_column_text css=””]<\/p>\n

Abstract<\/h3>\n
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Purpose:\u00a0<\/strong>The aim of the present work was to develop a fibrin membrane using plasma rich in growth factors (PRGF) technology with improved optical properties to be used for the treatment of ocular surface diseases.<\/p>\n

Basic procedures:\u00a0<\/strong>TBlood was drawn from three healthy donors, and the volume of PRGF obtained from each donor was divided into two main groups: i) PRGF or ii) platelet-poor plasma (PPP). Each membrane was then used pure or diluted to 90 %, 80 %, 70 %, 60 % and 50 %. The transparency of each of the different membranes was evaluated. The degradation and morphological characterization of each membrane was also performed. Finally, a stability study of the different fibrin membranes was performed.<\/p>\n

Main findings:\u00a0<\/strong>The transmittance test showed that the fibrin membrane with the best optical characteristics was obtained after removal of platelets and dilution of fibrin to 50 % (50 % PPP). No significant differences (p > 0.05) were observed between the different membranes in the fibrin degradation test. The stability test showed that the membrane at 50 % PPP retains its optical and physical characteristics after storage at – 20 \u00b0C for 1 month compared to storage at 4 \u00b0C.<\/p>\n

Principal conclusions:\u00a0<\/strong>TThe present study describes the development and characterization of a new fibrin membrane with improved optical characteristics while maintaining mechanical and biological characteristics. The physical and mechanical properties of the newly developed membrane are preserved after storage for at least 1 month at – 20 \u00b0C.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

Keywords:\u00a0<\/strong>Fibrin membrane; Ocular surface diseases; Optical characteristics; PRP; Plasma rich in growth factors; Platelet rich plasma.[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row content_placement=”middle” content_text_aligment=”center”][vc_column][\/vc_column][\/vc_row][vc_row][vc_column]\n Aceder ao artigo completo<\/span>\n <\/a>[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Ann Anat. 2023 Jun;248:152071.<\/strong>
\nThe aim of the present work was to develop a fibrin membrane using plasma rich in growth factors (PRGF) technology with improved optical properties to be used for the treatment of ocular surface diseases.<\/p>\n","protected":false},"author":2002,"featured_media":40772,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[158],"tags":[],"class_list":["post-40781","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina-regenerativa-pt-pt"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/posts\/40781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/users\/2002"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/comments?post=40781"}],"version-history":[{"count":1,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/posts\/40781\/revisions"}],"predecessor-version":[{"id":40782,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/posts\/40781\/revisions\/40782"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/media\/40772"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/media?parent=40781"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/categories?post=40781"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/pt-pt\/wp-json\/wp\/v2\/tags?post=40781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}