{"id":47921,"date":"2023-05-01T09:05:41","date_gmt":"2023-05-01T08:05:41","guid":{"rendered":"https:\/\/www.btitrainingcenter.com\/rwc-update-intraoperative-fluorescein-angiography-plasma-rich-in-growth-factor-as-adjuvant-to-vitrectomy-in-high-myopic-retinal-detachment-associated-with-full-thickness-macular-hole-giant-tear-of\/"},"modified":"2026-04-10T15:28:08","modified_gmt":"2026-04-10T14:28:08","slug":"rwc-update-intraoperative-fluorescein-angiography-plasma-rich-in-growth-factor-as-adjuvant-to-vitrectomy-in-high-myopic-retinal-detachment-associated-with-full-thickness-macular-hole-giant-tear-of","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/it\/rwc-update-intraoperative-fluorescein-angiography-plasma-rich-in-growth-factor-as-adjuvant-to-vitrectomy-in-high-myopic-retinal-detachment-associated-with-full-thickness-macular-hole-giant-tear-of\/","title":{"rendered":"RWC Update: Intraoperative Fluorescein Angiography, Plasma Rich in Growth Factor as Adjuvant to Vitrectomy in High Myopic Retinal Detachment Associated with Full-Thickness Macular Hole, Giant Tear of the Retinal Pigment Epithelium"},"content":{"rendered":"

[vc_row disable_element=”yes” content_text_aligment=”left” row_background_lines=”no”][vc_column][vc_column_text css=””]Retinal detachment (RD) may be a dreadful complication of full-thickness macular hole (FTMH) in high myopic eyes.\u00a0 Although the pathophysiology of this condition has yet to be fully elucidated, various factors are believed to play a role in its formation, including tangential traction due to abnormally rigid internal limiting membrane (ILM) and retinal vessels, anteroposterior traction due to steep staphyloma, and insufficient retinal adhesion due to defective retinal pigment epithelium (RPE) pump.<\/p>\n

This condition may be approached with different surgical techniques, ab interno or ab externo including macular buckling, standard ILM peeling, ILM peeling with inverted flap technique, free ILM flap insertion, and the use of different extraocular tissues\/compounds such as amniotic membrane plugs and anterior capsule plug with the goal to fill and close the macular hole (MH), facilitating the reattachment of the retina. Autologous retinal transplant has also been proposed as a useful resource in selected cases.<\/p>\n

Posterior staphylomas, extreme axial lengths, thin retina, insufficient ILM visualization due to poor contrast, and suboptimal dying are all factors that may negatively affect ILM peeling maneuvers in high myopic eyes. However, although difficult to perform, inverted flap and free flap techniques have significantly boosted idiopathic MH closure rate when compared to standard ILM peeling, according to multiple reports. In fact, primary closure rate increased from 33% to 56% after ILM peel only, to 80% to 100% with inverted flap.<\/p>\n

The inverted flap technique implies the preservation of sufficient ILM at the hole borders to create a scaffold in which glial migration and proliferation may occur, creating a combined mechanical plus biological effect. However, although effective, inverted flap is a technique implying increased surgical manipulation compared to standard ILM peel.
\nIn the case of detached retina, surgical maneuvers are even more challenging as the retina is much more mobile, and in such cases the use of perfluorocarbon liquid to stabilize the retina may be necessary.[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n

Figures<\/h3>\n

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\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>[vc_empty_space height=”50px”][\/vc_column][\/vc_row][vc_row][vc_column]\n Scarica articolo<\/span>\n <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Ophthalmic Surgery, Lasers and Imaging Retina Volume 54, Number 5 Pages 259 – 264<\/strong><\/p>\n","protected":false},"author":2002,"featured_media":47910,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[157],"tags":[],"class_list":["post-47921","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina-rigenerativa"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/47921","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/users\/2002"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/comments?post=47921"}],"version-history":[{"count":1,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/47921\/revisions"}],"predecessor-version":[{"id":47922,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/47921\/revisions\/47922"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/media\/47910"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/media?parent=47921"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/categories?post=47921"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/tags?post=47921"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}