
{"id":47381,"date":"2014-12-15T13:20:25","date_gmt":"2014-12-15T12:20:25","guid":{"rendered":"https:\/\/www.btitrainingcenter.com\/intraosseous-infiltration-of-platelet-rich-plasma-for-severe-knee-osteoarthritis\/"},"modified":"2026-04-08T08:53:57","modified_gmt":"2026-04-08T07:53:57","slug":"intraosseous-infiltration-of-platelet-rich-plasma-for-severe-knee-osteoarthritis","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/it\/intraosseous-infiltration-of-platelet-rich-plasma-for-severe-knee-osteoarthritis\/","title":{"rendered":"Intraosseous infiltration of platelet-rich plasma for severe knee osteoarthritis"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row gap=&#8221;20&#8243; content_text_aligment=&#8221;left&#8221; row_background_lines=&#8221;no&#8221;][vc_column width=&#8221;2\/3&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3 class=\"title\">Abstract<\/h3>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p>We describe a new technique of platelet-rich plasma (PRP) infiltration for the treatment of severe knee osteoarthritis. PRP intra-articular infiltration is a promising treatment for knee osteoarthritis, but it still has some limitations in high-degree osteoarthritis. Diagnosis of osteoarthritis is based on clinical and radiographic findings, and patients with grade III or IV knee tibiofemoral osteoarthritis based on the Ahlb\u00e4ck scale are considered candidates for this technique. The technique consists of performing intraosseous infiltration of PRP into the subchondral bone, which acts on this tissue and consequently on cartilage-bone communication. Although the intraosseous injection hinders the conventional knee intra-articular infiltration, it allows an extension of the range of action of the PRP, which acts directly on the subchondral bone, which is involved in the progression of osteoarthritis. Thus this technique involves a new administration of PRP that can delay knee arthroplasty; moreover, it can be applied for not only severe osteoarthritis but also other pathologies in which the subchondral bone is critical in the etiology, such as necrosis and osteochondral lesions.<\/p><\/div>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space][vc_empty_space height=&#8221;15px&#8221;][vc_column_text]<\/p>\n<h3>Figures<\/h3>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1775632640233{margin-top: 75px !important;margin-right: 5% !important;margin-left: 30px !important;padding-right: 20px !important;padding-bottom: 10px !important;padding-left: 20px !important;background-color: #F6F6F6 !important;border-radius: 25px !important;}&#8221;]<div class=\"qodef-animation-holder qodef-element-from-fade\" data-animation=\"qodef-element-from-fade\" data-animation-delay=\"300\"><div class=\"qodef-animation-inner\">[vc_column_text css=&#8221;&#8221;]<em>Accedi alla brochure di BTI:<\/em>[\/vc_column_text][vc_single_image image=&#8221;45493&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; css=&#8221;.vc_custom_1775634522931{margin-top: -10px !important;}&#8221; link=&#8221;https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/2.-USA_OSTEOARTRITIS_TECNICA.pdf&#8221;]<a itemprop=\"url\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/2.-USA_OSTEOARTRITIS_TECNICA.pdf\" target=\"_blank\" style=\"margin: 12px 5px 7px 35px\" class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2 text12\"  >\n    <span class=\"qodef-btn-text\">Accedi al pdf<\/span>\n    <\/a><\/div><\/div>[\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221; content_text_aligment=&#8221;center&#8221;][vc_column]<div class=\"qodef-image-gallery qodef-grid-list qodef-disable-bottom-space  qodef-ig-grid-type qodef-four-columns qodef-tiny-space  qodef-image-behavior-lightbox\">\n\t<div class=\"qodef-ig-inner qodef-outer-space\">\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr1.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-853]\" title=\"&lt;strong&gt;Fig 1.&lt;\/strong&gt; (A) The platelet-rich plasma (PRP) intraosseous infiltration of a knee with severe femorotibial osteoarthritis is performed into the medial tibial plateau (1) and medial femoral condyle (2). (B) If the patient presents with femoropatellar osteoarthritis, the approach is external and the patella (3) and trochlea (4) are infiltrated. Before these intraosseous injections are performed, conventional knee intra-articular infiltration of PRP is conducted.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr1-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr2.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-853]\" title=\"&lt;strong&gt;Fig 2.&lt;\/strong&gt; After the patient is positioned supine on the operating room table, (A) intra-articular infiltration is performed into the joint through the external patellar wing, centered in the central region of the patella in the craniocaudal plane; (B) the infiltration is directed into the midpoint area of the femoropatellar region using an external approach and preventing infiltration into the synovial membrane (asterisk). (C, D) Intraosseous tibial plateau infiltration is conducted into the medial tibial plateau, just to its middle area. The arrow indicates the trocar. (E, F) Concerning intraosseous femoral condyle infiltration, a trocar (arrow) is applied to the thickness of the medial femoral condyle, as far as the middle area of the medial condyle.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr2-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr3.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-853]\" title=\"&lt;strong&gt;Fig 3.&lt;\/strong&gt; Patients are diagnosed with osteoarthritis (OA) based on physical examination findings and imaging techniques, using scales such as the Ahlb\u00e4ck scale or Kellgren-Lawrence scale. Depending on the osteoarthritis grade, different treatments can be applied. If the patient presents with Ahlb\u00e4ck grade I or II, we propose a classic treatment or intra-articular infiltration of platelet-rich plasma (PRP). If the patient presents with grade III or IV, we apply intraosseous infiltration with 2 intra-articular infiltrations in the subsequent weeks. If the patient presents with grade V, he or she undergoes a total knee arthroplasty.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr3-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr4.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-853]\" title=\"&lt;strong&gt;Fig 4.&lt;\/strong&gt; (A) Communications between cartilage and subchondral bone are more pronounced in degenerated cartilage. (B) The platelet-rich plasma infiltrated into subchondral bone flows through the degenerated zones, and because of its viscous consistency, (C) it remains in the area, creating a matrix (asterisk).\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/gr4-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>[vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column]<a itemprop=\"url\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/2.-main.pdf\" target=\"_blank\"  class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2\"  >\n    <span class=\"qodef-btn-text\">Scarica articolo<\/span>\n    <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><strong>Arthrosc Tech. 2014 Dec 15;3(6):e713-7. <\/strong><br \/>\nWe describe a new technique of platelet-rich plasma (PRP) infiltration for the treatment of severe knee osteoarthritis. PRP intra-articular infiltration is a promising treatment for knee osteoarthritis, but it still has some limitations in high-degree osteoarthritis. Diagnosis of osteoarthritis is based on clinical and radiographic findings, and patients with grade III or IV knee tibiofemoral osteoarthritis based on the Ahlb\u00e4ck scale are considered candidates for this technique.<\/p>\n","protected":false},"author":2002,"featured_media":45260,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[157],"tags":[],"class_list":["post-47381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina-rigenerativa"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/47381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/users\/2002"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/comments?post=47381"}],"version-history":[{"count":4,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/47381\/revisions"}],"predecessor-version":[{"id":47393,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/47381\/revisions\/47393"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/media\/45260"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/media?parent=47381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/categories?post=47381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/tags?post=47381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}