{"id":34080,"date":"2023-10-10T10:26:35","date_gmt":"2023-10-10T09:26:35","guid":{"rendered":"https:\/\/www.btitrainingcenter.com\/plasma-rich-in-growth-factors-prgf-in-the-treatment-of-patients-with-chronic-cervical-and-lumbar-pain-a-prospective-observational-clinical-study\/"},"modified":"2025-01-30T10:06:24","modified_gmt":"2025-01-30T09:06:24","slug":"plasma-rich-in-growth-factors-prgf-in-the-treatment-of-patients-with-chronic-cervical-and-lumbar-pain-a-prospective-observational-clinical-study","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/it\/plasma-rich-in-growth-factors-prgf-in-the-treatment-of-patients-with-chronic-cervical-and-lumbar-pain-a-prospective-observational-clinical-study\/","title":{"rendered":"Plasma Rich in Growth Factors (PRGF) in the Treatment of Patients With Chronic Cervical and Lumbar Pain: A Prospective Observational Clinical Study"},"content":{"rendered":"

[vc_row content_text_aligment=”left” row_background_lines=”no”][vc_column][vc_column_text css=””]<\/p>\n

Abstract<\/h3>\n
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Background:<\/strong> Chronic back pain is a long-lasting disorder, whose main source of pain is often the intervertebral disc that undergoes a degenerative process associated with low-grade inflammation, leading to a reduced quality of life.<\/p>\n

Objetives:\u00a0<\/strong>The aim of our study was to assess the efficacy of intradiscal and epidural injections of plasma rich in growth factors (PRGF) in patients with chronic clinical symptoms due to intervertebral disc (IVD) degeneration.<\/p>\n

Study design:\u00a0<\/strong>Prospective observational study.<\/p>\n

Setting:\u00a0<\/strong>A single spine unit in a private clinic.<\/p>\n

Methods: <\/strong>Thirty-two patients with cervical and lumbar chronic pain due to IVD degeneration were treated with 2 or 3 series of intradiscal and epidural PRGF infiltrations with 2 weeks between each procedure. The procedures were performed under fluoroscopic guidance and grade 3 sedation in an operating theater. Treatment efficacy was evaluated using the Spine Tango Core Outcome Measure Index questionnaire, Numeric Rating Scale for back pain, and the Oswestry Disability Index questionnaire. In addition, the number of patients who successfully achieved the minimal clinically important change was also determined. These assessments were evaluated at pretreatment (baseline) and at one, 3, and 6 months posttreatment.<\/p>\n

Results: <\/strong>The Oswestry Disability Index, COMI Spine Tango Core Outcome Measure Index total score, and Numeric Rating Scale showed a statistically significant reduction from the baseline level to the posttreatment first month, third month, and sixth month (P < 0.001). Moreover, 78.1% of the patients reached a pain reduction superior to 30% one month posttreatment, and 87.5% at 6 months posttreatment, which is considered as a clinically significant improvement.<\/p>\n

Limitations:\u00a0<\/strong>This study was prospective and did not have a control group. Only patient-reported outcomes were evaluated.<\/p>\n

Conclusions: <\/strong>This observational, prospective study of patients with chronic back pain showed that 2-3 intradiscal and epidural injections of PRGF significantly decreased pain and disability at one month posttreatment and this improvement was maintained, and in some patients even improved, at 3, and 6 months posttreatment.<\/p>\n

Keywords:\u00a0<\/strong>back pain; degenerative disc disease; growth factors; intervertebral disc degeneration; plasma rich in growth factors; regenerative medicine; Platelet-rich plasma.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row content_placement=”middle” content_text_aligment=”center”][vc_column][vc_empty_space height=”50px”][\/vc_column][\/vc_row][vc_row][vc_column]\n Scarica articolo<\/span>\n <\/a>[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Pain Physician. 2023 Oct;26(6):E725-E736.<\/strong> The aim of our study was to assess the efficacy of intradiscal and epidural injections of plasma rich in growth factors (PRGF) in patients with chronic clinical symptoms due to intervertebral disc (IVD) degeneration.<\/p>\n","protected":false},"author":2002,"featured_media":34074,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[157],"tags":[],"class_list":["post-34080","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina-rigenerativa"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/34080","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/users\/2002"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/comments?post=34080"}],"version-history":[{"count":2,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/34080\/revisions"}],"predecessor-version":[{"id":35581,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/posts\/34080\/revisions\/35581"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/media\/34074"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/media?parent=34080"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/categories?post=34080"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/it\/wp-json\/wp\/v2\/tags?post=34080"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}