
{"id":47697,"date":"2011-02-01T10:02:51","date_gmt":"2011-02-01T09:02:51","guid":{"rendered":"https:\/\/www.btitrainingcenter.com\/efficacy-and-safety-of-plasma-rich-in-growth-factors-prgf-in-facial-skin-regeneration-a-randomized-controlled-clinical-trial-with-hyaluronic-acid\/"},"modified":"2026-04-09T12:29:37","modified_gmt":"2026-04-09T11:29:37","slug":"efficacy-and-safety-of-plasma-rich-in-growth-factors-prgf-in-facial-skin-regeneration-a-randomized-controlled-clinical-trial-with-hyaluronic-acid","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/fr\/efficacy-and-safety-of-plasma-rich-in-growth-factors-prgf-in-facial-skin-regeneration-a-randomized-controlled-clinical-trial-with-hyaluronic-acid\/","title":{"rendered":"Efficacy and Safety of Plasma Rich in Growth Factors (PRGF) in Facial Skin Regeneration: A Randomized, Controlled Clinical Trial with Hyaluronic Acid"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row gap=&#8221;20&#8243; content_text_aligment=&#8221;left&#8221; row_background_lines=&#8221;no&#8221;][vc_column width=&#8221;2\/3&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3 class=\"title\">Abstract<\/h3>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p><strong class=\"sub-title\">Purpose:\u00a0<\/strong>The present study is the first clinical randomized controlled assay with hyaluronic acid (HA) registered in Europe to show efficacy and safety of PRGF for the treatment of skin ageing.<\/p>\n<p><strong class=\"sub-title\">Methods:\u00a0<\/strong>A total of 100 patients of different phototypes (I-IV) and ages (31 -65 y.o.) were recruited for the assay. Randomized patients were treated intradermically with either HA or PRGF. HA was used once every month while<br \/>\nPRGF was applied once every two weeks for a total of 3 sessions of each treatment. Two follow up visits were scheduled for each patient group at 3 and 6 months post-treatment. Patient satisfaction was assessed by means of \u201cLiquert scale\u201d. Corneometry and patient satisfaction were two of the variables measured at each treatment session and on the 3 and 6 months follow up visits<\/p>\n<p><strong class=\"sub-title\">Results:\u00a0<\/strong>Corneometry measurements showed a significant improvement in skin hydration at both 3 and 6 moths. Furthermore, the effect of PRGF at 6 months remained 11% higher than initial measurement before treatment while only 3 % improvement was observed after HA treatment. The number of very satisfied patients was 73% higher in the group treated with PRGF.<\/p>\n<p><strong class=\"sub-title\">Conclusions:\u00a0<\/strong>Patients treated with PRGF showed higher skin hydration and referred higher levels of satisfaction than those treated with HA. These effects were already observed during the first month of treatment.<\/p>\n<\/div>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1775727185936{margin-top: 80px !important;margin-right: 5% !important;margin-left: 30px !important;padding-right: 20px !important;padding-bottom: 20px !important;padding-left: 20px !important;background-color: #F6F6F6 !important;border-radius: 25px !important;}&#8221;]<div class=\"qodef-animation-holder qodef-element-from-fade\" data-animation=\"qodef-element-from-fade\" data-animation-delay=\"300\"><div class=\"qodef-animation-inner\">[vc_column_text css=&#8221;&#8221;]<em>Acc\u00e9der \u00e0 la brochure de BTI:<\/em>[\/vc_column_text][vc_single_image image=&#8221;47540&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; css=&#8221;&#8221; link=&#8221;https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/2.-USA_Rejuvenecimiento_FACIAL.pdf&#8221;]<a itemprop=\"url\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/2.-USA_Rejuvenecimiento_FACIAL.pdf\" target=\"_blank\" style=\"margin: 15px 5px 3px 33px\" class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2 text12\"  >\n    <span class=\"qodef-btn-text\">Access to pdf<\/span>\n    <\/a><\/div><\/div>[\/vc_column][\/vc_row][vc_row][vc_column]<a itemprop=\"url\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/04.-2011-AECEPFebrero2011-ENSAYOCLINICOPRGFVSAH-1.pdf\" target=\"_blank\"  class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2\"  >\n    <span class=\"qodef-btn-text\">T\u00e9l\u00e9charger l&#039;article<\/span>\n    <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>PRGF efficacy in facial rejuvenation.<\/p>\n","protected":false},"author":2002,"featured_media":47540,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[155],"tags":[],"class_list":["post-47697","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medecine-regenerative"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/47697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/users\/2002"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/comments?post=47697"}],"version-history":[{"count":2,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/47697\/revisions"}],"predecessor-version":[{"id":47699,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/47697\/revisions\/47699"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/media\/47540"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/media?parent=47697"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/categories?post=47697"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/tags?post=47697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}