{"id":20356,"date":"2021-01-22T09:00:15","date_gmt":"2021-01-22T09:00:15","guid":{"rendered":"https:\/\/dev2.btitrainingcenter.com\/plasma-rich-in-growth-factors-versus-mitomycin-c-in-photorefractive-keratectomy\/"},"modified":"2025-04-09T16:13:16","modified_gmt":"2025-04-09T15:13:16","slug":"plasma-rich-in-growth-factors-versus-mitomycin-c-in-photorefractive-keratectomy","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/fr\/plasma-rich-in-growth-factors-versus-mitomycin-c-in-photorefractive-keratectomy\/","title":{"rendered":"Plasma rich in growth factors versus Mitomycin C in photorefractive keratectomy"},"content":{"rendered":"

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Abstract<\/h3>\n
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To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) in photorefractive keratectomy (PRK) versus Mitomycin C (MMC).This is a comparative, longitudinal and retrospective case-control study (MMC vs PRGF), in patients with a spherical correction from -0.25 to -8.00 D and cylinder correction from -0.25 to -3.00. The uncorrected distance visual acuity (UDVA), refractive efficacy and safety indices, and changes in endothelial cell density were evaluated. The predictability was assessed with the postoperative manifest spherical equivalent.Forty-four patients (72 eyes) were treated with MMC and twenty-five patients (45 eyes) with PRGF. The final UDVA (LogMar) in MMC was 0.029 \u00b1 0.065 and in PRGF it was 0.028 \u00b1 0.048 (p = 0.383). The efficacy index for MMC was 0.98 \u00b1 0.10 and 1.10 \u00b1 0.46 for patients treated with PRGF (p = 0.062). The safety index for MMC was 1.03 \u00b1 0.11 and 1.12 \u00b1 0.46 (p = 0.158) for PRGF group. The change percentage of endothelial cell density was 0.9 \u00b1 11.6 for MMC and 4.3 \u00b1 13.1 for PRGF (p = 0.593). The predictability for MMC was 92.1% and for the PRGF was 91.9% (p = 0.976). Hyperemia, eye pain and superficial keratitis were observed in 11.1% of the MMC group; no adverse events were observed with the PRGF.The use of PRGF in PRK surgery is as effective as MMC. The PRGF shows a better safety profile than MMC for its intraoperative use in PRK.<\/p>\n<\/div>\n<\/div>\n

Copyright \u00a9 2021 the Author(s). Published by Wolters Kluwer Health, Inc.<\/em><\/p>\n<\/div>\n<\/div>\n

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Figures<\/h3>\n

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Medicine (Baltimore). 2021 Jan 22;100(3):e24139.<\/strong> To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) in photorefractive keratectomy (PRK) versus Mitomycin C (MMC).This is a comparative, longitudinal and retrospective case-control study (MMC vs PRGF), in patients with a spherical correction from -0.25 to -8.00 D and cylinder correction from -0.25 to -3.00<\/p>\n","protected":false},"author":1,"featured_media":19999,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[155],"tags":[405,406,407,408],"class_list":["post-20356","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medecine-regenerative","tag-apnea-fr","tag-implantologia-fr","tag-medicina-fr","tag-salud-fr"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/20356","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/comments?post=20356"}],"version-history":[{"count":2,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/20356\/revisions"}],"predecessor-version":[{"id":37589,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/20356\/revisions\/37589"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/media\/19999"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/media?parent=20356"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/categories?post=20356"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/tags?post=20356"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}