
{"id":20301,"date":"2022-03-01T09:00:09","date_gmt":"2022-03-01T09:00:09","guid":{"rendered":"https:\/\/dev2.btitrainingcenter.com\/current-opinion-on-the-role-of-vitamin-d-supplementation-in-respiratory-infections-and-asthma-copd-exacerbations-a-need-to-establish-publication-guidelines-for-overcoming-the-unpublished-data\/"},"modified":"2025-01-30T10:23:49","modified_gmt":"2025-01-30T09:23:49","slug":"current-opinion-on-the-role-of-vitamin-d-supplementation-in-respiratory-infections-and-asthma-copd-exacerbations-a-need-to-establish-publication-guidelines-for-overcoming-the-unpublished-data","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/fr\/current-opinion-on-the-role-of-vitamin-d-supplementation-in-respiratory-infections-and-asthma-copd-exacerbations-a-need-to-establish-publication-guidelines-for-overcoming-the-unpublished-data\/","title":{"rendered":"Current opinion on the role of vitamin D supplementation in respiratory infections and asthma\/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row content_text_aligment=&#8221;left&#8221; row_background_lines=&#8221;no&#8221;][vc_column][vc_column_text]<\/p>\n<h3 class=\"title\">Abstract<\/h3>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<div id=\"abstract\" class=\"abstract\">\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p><strong class=\"sub-title\">Background &amp; aims:\u00a0<\/strong>The role of prophylactic vitamin D supplementation in prevention and treatment of respiratory infections and other related pathologies has been extensively explored with conflicting results. The aim of this systematic review and meta-analysis was to evaluate the prophylactic and therapeutic effects of vitamin D administration on respiratory infections.<\/p>\n<p><strong class=\"sub-title\">Methods:\u00a0<\/strong>A systematic search was performed and randomized controlled trials (RCTs) of vitamin D supplementation and a total of 65 RCTs involving 50,554 participants were included.<\/p>\n<p><strong class=\"sub-title\">Results:\u00a0<\/strong>The overall incidence of respiratory infections in terms of count data (OR: 0.87; 95%CI [0.80-0.95]; p = 0.0028; I<sup>2<\/sup>\u00a0= 43%) and event rate (IRR: 0.81; 95%CI [0.70-0.95]; p = 0.010; I<sup>2<\/sup>\u00a0= 79%) was significantly reduced in the intervention group. However, no effect of vitamin D on duration or upper respiratory tract infection severity was observed following the overall analysis. Subgroup analyses revealed more details regarding the protective effect of particular dose ranges, administration frequencies and trial durations on different disease types.<\/p>\n<p><strong class=\"sub-title\">Conclusions:\u00a0<\/strong>Despite between-study heterogeneity was high for most outcomes and publication bias may have led to an effect size overestimation of incidence count data, vitamin D supplementation could be beneficial in improving resistance to overall respiratory infections, particularly when administered on a daily basis.<\/p>\n<\/div>\n<p><strong class=\"sub-title\">Keywords:\u00a0<\/strong>Cholecalciferol; Meta-analysis; Prophylaxis; Systematic review.<\/p>\n<\/div>\n<p id=\"copyright\" class=\"copyright\"><em>Copyright \u00a9 2022 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.<\/em><\/p>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column]<a itemprop=\"url\" href=\"https:\/\/www.clinicalnutritionjournal.com\/article\/S0261-5614(22)00042-5\/fulltext\" target=\"_blank\"  class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2\"  >\n    <span class=\"qodef-btn-text\">Acc\u00e9der \u00e0 l&#039;article complet<\/span>\n    <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><strong>Clin Nutr. 2022 Mar;41(3):755-777.<\/strong> The role of prophylactic vitamin D supplementation in prevention and treatment of respiratory infections and other related pathologies has been extensively explored with conflicting results. The aim of this systematic review and meta-analysis was to evaluate the prophylactic and therapeutic effects of vitamin D administration on respiratory infections.<\/p>\n","protected":false},"author":1,"featured_media":19069,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[180],"tags":[406,407,408],"class_list":["post-20301","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-apnee-du-sommeil-et-ronflement","tag-implantologia-fr","tag-medicina-fr","tag-salud-fr"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/20301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/comments?post=20301"}],"version-history":[{"count":1,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/20301\/revisions"}],"predecessor-version":[{"id":35610,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/posts\/20301\/revisions\/35610"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/media\/19069"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/media?parent=20301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/categories?post=20301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/fr\/wp-json\/wp\/v2\/tags?post=20301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}