
{"id":18019,"date":"2015-08-04T09:00:55","date_gmt":"2015-08-04T09:00:55","guid":{"rendered":"https:\/\/dev2.btitrainingcenter.com\/mandibular-advancement-treatment-sleep-apnea-crossover\/"},"modified":"2025-04-09T16:10:19","modified_gmt":"2025-04-09T15:10:19","slug":"mandibular-advancement-treatment-sleep-apnea-crossover","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/en\/mandibular-advancement-treatment-sleep-apnea-crossover\/","title":{"rendered":"Efficacy of mandibular advancement device in the treatment of obstructive sleep apnea syndrome: A randomized controlled crossover clinical trial"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row content_text_aligment=&#8221;left&#8221; row_background_lines=&#8221;no&#8221;][vc_column][vc_column_text]<\/p>\n<h3 class=\"title\">Abstract<\/h3>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p><strong class=\"sub-title\">Background:\u00a0<\/strong>Evaluation of the efficacy and safety of a mandibular advancement device (MAD) (KlearwayTM) in the treatment of mild-to-moderate obstructive sleep apnea and chronic roncopathy.<\/p>\n<p><strong class=\"sub-title\">Material and methods:\u00a0<\/strong>A randomized, placebo-controlled, double blinded, and crossover clinical trial was conducted. Placebo device (PD) defined as a splint in the centric occlusion that did not induce a mandibular advancement served as a control. The mandible was advanced to the maximum tolerable distance or to a minimum of 65% of the maximum protrusion. After each sequence of treatment, patients were assessed by questionnaires, conventional polysomnography, and objective measurement of snoring at the patient&#8217;s own home.<\/p>\n<p><strong class=\"sub-title\">Results:\u00a0<\/strong>Forty two patients participated in the study and 38 completed the study. Patients mean age was 46 \u00b19 years and the 79% were males. The mean mandibular advancement was 8.6 \u00b12.8 mm. Patients used the MAD and the PD for 6.4 +2.4 hours and 6.2 +2.0 hours, respectively. Secondary effects (mostly mild) occurred in the 85.7% and the 86.8% of the users of MAD and PD, respectively. The MAD induced a decrease in the apnea-hypopnea index (AHI) from 15.3 +10.2 to 11.9 +15.5. The 50% reduction in the AHI was achieved in the 46.2% and the 18.4% of the patients treated with MAD and PD, respectively. The use of the MAD induced a reduction in the AHI by 3.4 +15.9 while the PD induced an increase by 10.6 +26.1. The subjective evaluation of the roncopathy indicated an improvement by the MAD and an increase in the perceptive quality of sleep. However, the objective evaluation of the roncopathy did not show significant improvements.<\/p>\n<p><strong class=\"sub-title\">Conclusions:\u00a0<\/strong>The use of MAD is efficient to reduce the AHI and improve subjectively the roncopathy. MAD could be considered in the treatment of mild-to-moderate OSA and chronic roncopathy.<\/p>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h3>Figures<\/h3>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221; content_text_aligment=&#8221;center&#8221;][vc_column]<div class=\"qodef-image-gallery qodef-grid-list qodef-disable-bottom-space  qodef-ig-grid-type qodef-three-columns qodef-tiny-space  qodef-image-behavior-lightbox\">\n\t<div class=\"qodef-ig-inner qodef-outer-space\">\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2022\/01\/medoral-20-e605-g001.jpeg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-283]\" title=\"&lt;strong&gt;Figure 1:&lt;\/strong&gt; Study flow chart.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2022\/01\/medoral-20-e605-g001-200x200.jpeg\" alt=\"Figure 1 Study flow chart.\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2022\/01\/medoral-20-e605-g002.jpeg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-283]\" title=\"&lt;strong&gt;Figure 2:&lt;\/strong&gt; Effects of the device on the apnea-hypopnea index (AHI). Basal time (BT), placebo device (PD) and Mandibular Advancement device (MAD).\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2022\/01\/medoral-20-e605-g002-200x200.jpeg\" alt=\"Figure 2 Effects of the device on the apnea-hypopnea index (AHI). Basal time (BT), placebo device (PD) and Mandibular Advancement device (MAD).\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2022\/01\/medoral-20-e605-g003.jpeg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-283]\" title=\"&lt;strong&gt;Figure 3:&lt;\/strong&gt; Effects of the device on the net change in the apnea-hypopnea index (AHI). The results were calculated as the difference between the AHI at basal time and the AHI after the use of the device. Placebo device (PD) and Mandibular Advancement device (MAD).\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2022\/01\/medoral-20-e605-g003-200x200.jpeg\" alt=\"Figure 3: Effects of the device on the net change in the apnea-hypopnea index (AHI). The results were calculated as the difference between the AHI at basal time and the AHI after the use of the device. Placebo device (PD) and Mandibular Advancement device (MAD).\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>[vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column]<a itemprop=\"url\" href=\"\/wp-content\/uploads\/2021\/08\/medoral-20-e605.pdf\" target=\"_blank\"  class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2\"  >\n    <span class=\"qodef-btn-text\">Download article<\/span>\n    <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><strong>Med Oral Patol Oral Cir Bucal. 2015 Sep 1;20(5):e605-15.<\/strong> The application of the counter-torque technique has been proposed as a conservative and atraumatic alternative for the explantation of nonmobile dental implants. The objective of this report is to assess the performance of this technique in a large number of patients.<\/p>\n","protected":false},"author":1,"featured_media":15255,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[179],"tags":[401,402,403,404],"class_list":["post-18019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sleep-apnea-and-snoring","tag-apnea-en","tag-implantologia-en","tag-medicina-en","tag-salud-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/posts\/18019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/comments?post=18019"}],"version-history":[{"count":2,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/posts\/18019\/revisions"}],"predecessor-version":[{"id":37583,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/posts\/18019\/revisions\/37583"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/media\/15255"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/media?parent=18019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/categories?post=18019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/en\/wp-json\/wp\/v2\/tags?post=18019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}