
{"id":20542,"date":"2021-12-06T09:00:12","date_gmt":"2021-12-06T09:00:12","guid":{"rendered":"https:\/\/dev2.btitrainingcenter.com\/membrane-of-plasma-rich-in-growth-factors-in-primary-pterygium-surgery-compared-to-amniotic-membrane-transplantation-and-conjunctival-autograft\/"},"modified":"2025-03-17T14:05:30","modified_gmt":"2025-03-17T13:05:30","slug":"membrane-of-plasma-rich-in-growth-factors-in-primary-pterygium-surgery-compared-to-amniotic-membrane-transplantation-and-conjunctival-autograft","status":"publish","type":"post","link":"https:\/\/www.btitrainingcenter.com\/de\/membrane-of-plasma-rich-in-growth-factors-in-primary-pterygium-surgery-compared-to-amniotic-membrane-transplantation-and-conjunctival-autograft\/","title":{"rendered":"Membrane of Plasma Rich in Growth Factors in Primary Pterygium Surgery Compared to Amniotic Membrane Transplantation and Conjunctival Autograft"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row content_text_aligment=&#8221;left&#8221; row_background_lines=&#8221;no&#8221;][vc_column][vc_column_text]<\/p>\n<h3 class=\"title\">Abstract<\/h3>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p>This prospective and comparative study aimed to compare the use of a conjunctival autograft (CAG), plasma rich in growth factors fibrin membrane (mPRGF) or amniotic membrane transplantation (AMT) in primary pterygium surgery. Patients were assigned for surgery with CAG (group A), mPRGF (group B), or AMT (group C). Pterygium recurrence, Best Corrected Visual Acuity (BCVA), graft size (measured with anterior segment optical coherence tomography (AS-OCT)), and ocular surface symptoms (visual analogue scale (VAS) and ocular surface disease index (OSDI)) were evaluated. Thirteen eyes in group A, 26 in group B, and 10 in group C were evaluated. No changes in BCVA (<i>p<\/i>\u00a0&gt; 0.05) were found. Recurrence cases for groups A, B, and C were none, two, and two, respectively, and three cases of pyogenic granulomas in group A. The horizontal\/vertical graft size was lower in group B vs group A (<i>p<\/i>\u00a0&lt; 0.05) from months 1 to 12. The improvement in VAS frequency for groups A, B, and C was: 35.5%, 86.2%, and 39.1%, respectively. The OSDI scale reduction for groups A, B, and C was: 12.7%, 39.0%, and 84.1%. The use of the three surgical techniques as a graft for primary pterygium surgery was safe and effective, showing similar results. The mPRGF graft represents an autologous novel approach for pterygium surgery.<\/p>\n<\/div>\n<p><strong class=\"sub-title\">Keywords:\u00a0<\/strong>PRGF; PRP; amniotic membrane transplantation; conjunctival autograft; plasma rich in growth factors; pterygium surgery.<\/p>\n<\/div>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h3>Figures<\/h3>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221; content_text_aligment=&#8221;center&#8221;][vc_column]<div class=\"qodef-image-gallery qodef-grid-list qodef-disable-bottom-space  qodef-ig-grid-type qodef-four-columns qodef-tiny-space  qodef-image-behavior-lightbox\">\n\t<div class=\"qodef-ig-inner qodef-outer-space\">\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g001.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-591]\" title=\"&lt;strong&gt;Figure 01&lt;\/strong&gt; Use of mPRGF in pterygium surgery. (A) Bare sclera after pterigium surgery, (B) mPRGF was placed over the bare sclera and it was cut according to the size of the resected tissue, (C) one or two drops of fibrin glue was added to the bare sclera, and (D) mPRGF was placed over the fibrin glue, approximating the edges between the conjunctiva and the mPRGF to allow the gluing between them.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g001-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g002.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-591]\" title=\"&lt;strong&gt;Figure 02&lt;\/strong&gt; Visual acuity and intraocular pressure in the three treatment groups. (A) BCVA: best corrected visual acuity; Group A: conjunctival autograft; Group B: membrane &#8211; plasma rich in growth factors; Group C: amniotic membrane. No significant differences were found in visual acuity between the three groups (p &gt; 0.05) during the follow-up time. (B). IOP: intraocular pressure; Group A: conjunctival autograft; Group B: membrane &#8211; plasma rich in growth factors; Group C: amniotic membrane. No significant differences were observed in IOP among the three groups (p &gt; 0.05) during the entire follow-up time.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g002-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g003.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-591]\" title=\"&lt;strong&gt;Figure 03&lt;\/strong&gt; OCT graft measurements (\u00b5m) for mPRGF. Basal: TL: thickness of the limbus, HS: horizontal size, THS: total horizontal size, and VS: vertical size. During the postoperative follow-up, the conjunctival restoration zone was measured: GCT: graft central thickness, GTL: graft thickness in the limbus, GHS: graft horizontal size (measured between the sclerocorneal limbus to the nasal area of the excised conjunctiva), and GVS: graft vertical size.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g003-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g004.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-591]\" title=\"&lt;strong&gt;Figure 04&lt;\/strong&gt; Clinical follow-up of a patient treated with mPRGF in pterygium surgery.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g004-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<div class=\"qodef-ig-image qodef-item-space\">\n\t\t\t\t<div class=\"qodef-ig-image-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<a itemprop=\"image\" class=\"qodef-ig-lightbox\" href=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g005.jpg\" data-rel=\"prettyPhoto[image_gallery_pretty_photo-591]\" title=\"&lt;strong&gt;Figure 05&lt;\/strong&gt; Visual analog scale. (A) Frequency. Group A: conjunctival autograft, Group B: membrane-plasma rich in growth factors, Group C: amniotic membrane. (B) Severity. Group A: conjunctival autograft, Group B: membrane-plasma rich in growth factors, Group C: amniotic membrane.\">\n\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.btitrainingcenter.com\/wp-content\/uploads\/2021\/08\/jcm-10-05711-g005-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>[vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column]<a itemprop=\"url\" href=\"\/wp-content\/uploads\/2021\/08\/jcm-10-05711.pdf\" target=\"_blank\"  class=\"qodef-btn qodef-btn-medium qodef-btn-solid btnWebRosa2\"  >\n    <span class=\"qodef-btn-text\">Artikel herunterladen<\/span>\n    <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><strong>J Clin Med. 2021 Dec 6;10(23):5711.<\/strong> This prospective and comparative study aimed to compare the use of a conjunctival autograft (CAG), plasma rich in growth factors fibrin membrane (mPRGF) or amniotic membrane transplantation (AMT) in primary pterygium surgery.<\/p>\n","protected":false},"author":1,"featured_media":19208,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[156],"tags":[409,410,411,412],"class_list":["post-20542","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-regenerative-medizin","tag-apnea-de","tag-implantologia-de","tag-medicina-de","tag-salud-de"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/posts\/20542","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/comments?post=20542"}],"version-history":[{"count":1,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/posts\/20542\/revisions"}],"predecessor-version":[{"id":36867,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/posts\/20542\/revisions\/36867"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/media\/19208"}],"wp:attachment":[{"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/media?parent=20542"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/categories?post=20542"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.btitrainingcenter.com\/de\/wp-json\/wp\/v2\/tags?post=20542"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}